I. BRIEF INTRODUCTION

Prof. Haibao Zhu

Ph.D. (Huazhong Agricultural University, China)

E-mail：zhuhaibao@stu.edu.cn

Educational Background:

Ph.D. From September 2004 to July 2009, Department of Clinical Veterinary Medicine, College of Veterinary Medicine and Science, Huazhong Agricultural University

Work Experience:

1) October 2020 present, Professor, Department of Biology, School of Science, Shantou University

2) From August 2016 to June 2020, Technical Director at Guangdong Chimeng Medical Technology Co., Ltd

3) From January 2015 to August 2016, I worked as a postdoctoral fellow in the Department of Biomedical Engineering at Georgia Institute of Technology/Rice University,

4) From November 2011 to August 2014, worked as a postdoctoral fellow at the National University of Singapore,

5) From October 2009 to October 2011, I worked as a postdoctoral fellow at the University of Oklahoma,

II.REASEARCH

Projects Undertaken:

Shantou University, Research Initiation Fund Project, NTF20030, Application of Membrane Localization CreER in the Study of Mouse Pancreatic Beta Cell Development Mechanism, 2021-2023, 800000, in progress, principal investigator.

Representative Paper:

1)Sheng Tong; Haibao Zhu; Gang Bao*; Magnetic iron oxide nanoparticles for Disease Detection and Therapy, Materials Today,2019,31:86-99.

2)Haibao Zhu#; Linlin Zhang#; Sheng Tong#; Ciaran M Lee; Harshavardhan Deshmukh; Gang Bao*; Spatial control of in vivo CRISPR-Cas9 genome editing via nanomagnets, Nature Biomedical engineering, 2019,3(2):126-136.(Highlighted in Science Translational Medicine, Editor’s choice: Magnets make target cells more attractive to CRISPR.Science Translational Medicine.10,eaaw0520,2018.Also highlighted in Nature Biomedical Engineering, News and Views: Local magnetic activation of CRISPR. Nature Biomedical engineering.3,83-84,2019)

3)Cia-Hin Lau#; Haibao Zhu#; Johan Chin-Kang Tay; Zhendong Li; Felix Chang Tay; Can Chen; Wee-Kiat Tan; Shouhui Du; Vic-Ki Sia; Rui-Zhe Phang; Shin-Yi Tang; Chiyun Yang; Zhixia Chi; Chieh-Ching Liang; Er Ning; Shu Wang*; Minimizing genetic recombination between repeat-variable di-residues (RVDs) for robust targeted genome engineering driven by the baculoviral-TALEN system, Molecular Therapy-Methods and Clinical Development, 2014,1,14050;doi:10.1038/mtm.2014.50.

4)Haibao Zhu#; Cia-Hin Lau#; Sal-Lee Goh; Qingle Liang; Can Chen; Shouhui Du;Rui-Zhe Phang; Felix Chang Tay; Wee-Kiat Tan; Zhendong Li; Johan Chin-Kang Tay; Weimin Fan; Shu Wang*; Baculoviral Transduction Facilitates TALEN-Mediated Targeted Transgene Integration and Cre/LoxP Cassette Exchange in Human-Induced Pluripotent Stem Cells, Nucleic Acids Res, 2013,41(19):e180.

5)Haibao Zhu#; Binrui Cao; Zipeng Zhen; Ayyagari Ananta Laxmi; Dong Li;Shaorong Liu; Chuanbin Mao*; Controlled growth and differentiation of MSCs on grooved films assembled from monodisperse biological nanofibers with genetically tunable surface chemistries, Biomaterials, 2011, 21,(32): 4744-4752.

Patents：

Haibao Zhu;Sheng Tong;Gang Bao*; A Magnet Switch for Controlling Gene Delivery in Vivo, 2019-03-12,(U.S.patent Number:10286073;PCT Number:15441089).