郑志鸿老师个人简历
姓名：郑志鸿
性别：男
出生年月：1991.04
办公地点：高水平实验楼A416
E-mail：zhengzh@stu.edu.cn
教育背景：
2014.09-2021.06，汕头大学，生物化学与分子生物学，博士
2010.09-2014.06，广东海洋大学，生物工程，学士
工作经历：
2023.12至今，汕头大学，讲师（汕头大学卓越人才计划-优秀青年人才）
2021.09-2023.12，汕头大学，博士后
主讲课程：
本科生课程：仪器分析实验（上）、生物学产业创新实验、营养免疫学
主要研究方向：
对虾免疫与病害防治
主持科研项目：
1、国家自然科学基金青年基金项目：对虾血蓝蛋白调控肝胰腺线粒体自噬的分子机制与免疫学意义（32202976），2023.01-2025.12，30万元，主持（在研）；
2、广东省自然科学基金-面上项目：对虾血蓝蛋白调控胃优势菌Photobacterium damselae和Chitinophaga polysaccharea丰度的分子机制与免疫学意义（2024A1515011419），2024.01-2026.12，15万元，主持（在研）；
3、汕头大学科研启动经费项目：血蓝蛋白调控胃Photobacterium damselae定植参与对虾抗弧菌感染的机制研究（NTF24022T），2024.01-2027.12，25万元（首期），主持（在研）；
4、中国博士后科学基金面上项目：对虾血蓝蛋白介导肝胰腺线粒体自噬发生的机制研究（2022M712013），2022.09-2023.08，8万元，主持（结题）。
论文发表（#代表并列第一作者，*代表通讯作者/共同通讯作者）：
1. Zheng ZH, Aweya JJ, Bao SY, Yao DF, Li SK, Tran NT, Ma HY, Zhang YL. The microbial composition of penaeid shrimps’ hepatopancreas is modulated by hemocyanin. The Journal of Immunology, 2021, 207(11): 2733-2743.
2. Zheng ZH#, Aweya JJ#, Wang F, Yao DF, Lun JS, Li SK, Ma HY, Zhang YL*. Acute Hepatopancreatic Necrosis Disease (AHPND) related microRNAs in Litopenaeus vannamei infected with AHPND-causing strain of Vibrio parahemolyticus. BMC Genomics, 2018, 19 (1), 1-11.
3. Zheng ZH#, Wang F#, Aweya JJ, Li RW, Yao DF, Zhong MQ, Li SK, Zhang YL*. Comparative transcriptomic analysis of shrimp hemocytes in response to acute hepatopancreas necrosis disease (AHPND) causing Vibrio parahemolyticus infection. Fish & Shellfish Immunology, 2018, 74, 10-18.
4. Ning P#, Zheng ZH#, Aweya JJ, Yao DF, Li SK, Ma HY, Wang F, Zhang YL*. Litopenaeus vannamei notch affects lipopolysaccharides induced reactive oxygen species. Developmental & Comparative Immunology, 2018, 81, 74-82.
5. Zheng ZH, Tang DY, Zhao WL, Wan ZT, Yu ML, Huang ZY, Li L, Aweya JJ, Zhang YL. NLRP3-like protein negatively regulates the expression of antimicrobial peptides in Penaeus vannamei hemocytes. Fish and Shellfish Immunology Reports, 2021, 2: 100039.
6. Zhou YQ, Aweya JJ, Huang ZS, Chen Y, Tang ZQ, Shi ZH, Zheng ZH*, Zhang YL*. The ELOVL6 homolog in Penaeus vannamei plays a dual role in fatty acid metabolism and immune response. Molecular Immunology, 2023, 164: 7-16.
7. Huang YQ, Tan DQ, Chen XY, Xia BH, Zhao YZ, Chen XL, Zhang YL, Zheng ZH*. Function of hemocyanin-mediated succinate dehydrogenase in glucose metabolism and immunity of Penaeus vannamei. Fish & Shellfish Immunology, 2024: 109689.
8. Wang ZY, Zhang, YL, Aweya JJ, Lin ZY, Yao DF*, Zheng ZH*. The histidine phosphatase LHPP of Penaeus vannamei is involved in shrimp hemocytes apoptosis. Fish and Shellfish Immunology Reports, 2023, 100109.
9. Aweya JJ*, Zheng ZH, Zheng XY, Yao DF, Zhang YL*. The expanding repertoire of immune-related molecules with antimicrobial activity in penaeid shrimps: a review. Reviews in Aquaculture, 2021, 13(4): 1907-1937.
10. Wang ZY, Aweya JJ, Yao DF, Zheng ZH, Wang CQ, Zhao YZ, Li SK, Zhang YL*. Taurine metabolism is modulated in Vibrio-infected Penaeus vannamei to shape shrimp antibacterial response and survival. Microbiome, 2022, 10(1): 1-19.
11. Nie JJ, Aweya JJ, Yu ZX, Zhou H, Wang F, Yao DF, Zheng ZH, Li SK, Ma HY, Zhang YL*. Deacetylation of K481 and K484 on Penaeid Shrimp Hemocyanin Is Critical for Antibacterial Activity. The Journal of Immunology, 2022, 209(3): 476-487.
12. Feng Q, Aweya JJ, Huang YQ, Zhang P, Wang F, Yao DF, Zheng ZH, Li EM, Zhang YL*. Dephosphorylation of T517 on Hemocyanin Is Required for Antibacterial Activity in Penaeus vannamei. The Journal of Immunology, 2023, 210(9): 1396-1407.
发明专利：
1）一种牛磺酸的应用，2023-08-18，中国，ZL 2022 1 0094520.8，已实施转让（5万元）；
2）一种抗菌肽及其应用，2020-05-15，中国，ZL 2017 10533310.3。
