工作经历：

主讲课程：

本科生课程：《水生毒理学》、《水生毒理学实验》、《海洋与人类生活》

研究生课程：《生物工程专业英语与科技论文写作》、《环境生态研究进展》

研究兴趣：

主要从事生态毒理学相关的研究，重点关注在全球气候变化的大背景下，水生生物对环境新污染物的响应和适应机制及其健康风险评价，研究兼具基础探索性与实际应用价值。主要研究内容为：

（1）环境新污染物的毒性效应与机制；

（2）多代影响与表观遗传调控；

（3）分子标志物的开发与应用；

（4）环境健康风险评价与管理。

欢迎入选菁英班和拔尖班的本科生加入开展课题。欢迎对以上研究领域感兴趣的本科生联系开展大学生创新创业大赛和毕业设计研究课题。尤其欢迎专业相关且有志攻读硕士和博士学位的学生联系（报考）加入。

科研项目：

[1] 国家自然科学青年基金项目 主持

[2] 汕头大学科研启动经费项目 主持

研究成果（*通讯作者）：

Publication full list: https://www.researchgate.net/profile/Jiezhang-Mo

[1] Mo J, Au DWT, Wan T, Shi J, Zhang G, Winkler C, Kong RYC*, Seemann F*. Multigenerational impacts of benzo[a]pyrene on bone modeling and remodeling in medaka (Oryzias latipes). Environmental Science & Technology, 2020, 54(19): 12271−12284. (IF 9.0, JCR Q1)

[2] Mo J, Au DWT, Guo J, Winkler C, Kong RYC*, Seemann F*. Benzo[a]pyrene osteotoxicity and the regulatory roles of genetic and epigenetic factors: A review. Critical Reviews in Environmental Science & Technology, 2022, 52(18): 3244−3282. (IF 11.8, JCR Q1)

[3] Mo J*, Chen Y, Lai KP, Seemann F, Liu W*. Benzo[a]pyrene osteotoxicity, neurotoxicity, and epigenetic effects in fishes and mammals: a review. Environmental Chemistry Letters, 2025, DOI: 10.1007/s10311-025-01859-y. (IF 20.4, JCR Q1)

[4] Mo J, Wan T, Au DWT, Shi JC, Tam N, Qin X, Cheung NKM, Lai KP, Winkler C, Kong RYC*, Seemann F*. Transgenerational bone toxicity in F3 medaka (Oryzias latipes) induced by ancestral benzo[a]pyrene exposure: Cellular and transcriptomic insights. Journal of Environmental Sciences, 2023, 127: 336−348. (IF 6.9, JCR Q1)

[5] Mo J, Lin D, Wang J, Li P, Liu W*. Apoptosis in HepG2 cells induced by zinc pyrithione via mitochondrial dysfunction pathway: Involvement of zinc accumulation and oxidative stress. Ecotoxicology & Environmental Safety, 2018, 161: 515−525. (IF 7.1, JCR Q1)

[6] Mo J, Qi Q, Hao Y, Lei Y, Guo J*. Transcriptional response of a green alga (Raphidocelis subcapitata) exposed to triclosan: Photosynthetic systems and DNA repair. Journal of Environmental Sciences, 2022, 111: 400−411. (IF 6.8, JCR Q1)

[7] Mo J, Ma Z, Yan S, Cheung NKM, Yang F, Yao X, Guo J*. Metabolomic profiles in a green alga (Raphidocelis subcapitata) following erythromycin treatment: ABC transporters and energy metabolism. Journal of Environmental Sciences, 2023, 124: 591−601. (IF 6.9, JCR Q1)

[8] Mo J, Han L, Lv Y, Chiang WLM, Fan R, Guo J*. (2023) Triclosan toxicity in a model cyanobacterium (Anabaena flos-aquae): Growth, photosynthesis and transcriptomic response. Journal of Environmental Sciences, 2023, 127: 82−90. (IF 6.9, JCR Q1)

[9] Mo J, Guo J*, Iwata H, Diamond J, Qu C, Xiong J, Han J. What approaches should be used to prioritize pharmaceutical and personal care products for research on environmental and human health exposure and effects? Environmental Toxicology & Chemistry, 2024, 43(3): 488−501. (IF 4.2, JCR Q2, Invited Review)

[10] Mo J*, Lv R, Qin X, Wu X, Chen H, Yan N, Wu Y, Liu W, Guo J. Mechanistic insights into hormesis induced by erythromycin in the marine alga Thalassiosira weissflogii. Ecotoxicology & Environmental Safety, 2023, 263: 115242. (IF 6.8, JCR Q1)

[11] Li Q, Lu D, Sun H, Guo J*, Mo J*. Tylosin toxicity in the alga Raphidocelis subcapitata revealed by integrated analyses of transcriptome and metabolome: Photosynthesis and DNA replication-coupled repair. Aquatic Toxicology, 2021, 239: 105964. (IF: 5.2 JCR Q1)

[12] Guo X, Chen H, Tong Y, Wu X, Qin X, Guo J, Li P, Wang Z, Liu W, Mo J*. A review on the antibiotic florfenicol: Occurrence, environmental fate, effects, and health risks. Environmental Research, 2023, 244: 117934. (IF 8.3, JCR Q1)

[13] Wu X, Tong Y, Li T, Guo J, Liu W, Mo J*. Metabolomic response of Thalassiosira weissflogii to erythromycin stress: Detoxification systems, steroidal metabolites, and energy metabolism. Plants, 2024, 13(3): 354. (IF 4.5, JCR Q1)

[14] Wu X, Jeong CB, Huang W, Ip JCH, Guo J, Lai KP, Liu W, Mo J*. Environmental occurrence, biological effects, and health implications of zinc pyrithione: A review. Marine Pollution Bulletin, 2024, 203: 116466. (IF 5.8, JCR Q1)

[15] Tang C, Qin X, Huang W, Debi S, Zhang Z, Guo J, Liu W, Mo J*. (2024). Environmental sources, fate, toxicological effects, and health risks of copper pyrithione: an overview. Frontiers of Environmental Science & Engineering, 2024, 18(11): 132. (IF 6.3, JCR Q1)

[16] Tong Y, Guo J, Li F, Lai KP, Mo J*. Antibiotic erythromycin in fish: Pharmacokinetics, effects, and health risks. Environmental Pollution, 2025, 373: 126203.  (IF 7.6, JCR Q1)

[17] Hong T, Mo J, Li T, Huang N, Liu W, Liang H, Pei P, Li P, Chen J, Du H*. Multi‐omics analysis reveals adaptation strategies of marine diatom to long‐term ocean warming: Resource allocation trade‐offs and epigenetic regulation. Plant, Cell & Environment, 2025, 48(7): 5089−5103. (IF 6.3, JCR Q1)

[18] Guo J, Mo J, Qi Q, Peng J, Qi G, Kanerva M, Iwata H, Li Q*. Prediction of adverse effects of effluents containing phenolic compounds in the Ba River on the ovary of fish (Hemiculter leucisculus) using transcriptomic and metabolomic analyses. Science of The Total Environment, 2021, 801: 149554.

[19] Qin X, Mo J, Lin H, Lyu R, Wu RSS, Kong RYC, Lai KP*. Embryonic developmental toxicity in marine medaka (Oryzias melastigma) caused by combined 17α-ethinylestradiol and hypoxic exposure. Frontiers of Environmental Science & Engineering, 2025, 19(4): 45.

[20] Wan T, Mo J, Au DWT, Qin X, Tam NYK, Kong RYC, Seemann F*. The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka. Epigenetics, 2023, 18(1): 2222246.

[21] Liang J, Li C, Mo J, Iwata H, Rehman F, Song J, Guo J*. Metatranscriptomic profiles reveal the biotransformation potential of azithromycin in river periphyton. Water Research, 2024, 251: 121140.

[22] Hong T, Huang N, Mo J, Chen Y, Li T, Du H*. Transcriptomic and physiological responses of a model diatom (Phaeodactylum tricornutum) to heat shock and heat selection. Ecological Indicators, 2023, 153: 110420.

[23] Ding N, Yu W, Mo J, Rehman F, Kasahara T, Guo, J*. Does exposure timing of macrolide antibiotics affect the development of river periphyton? Insights into the structure and function. Aquatic Toxicology, 2024, 275: 107070.

[24] Huang W*, Mo J, Li J, Wu K. Exploring developmental toxicity of microplastics and nanoplastics (MNPS): Insights from investigations using zebrafish embryos. Science of the Total Environment, 2024, 933: 173012.

[25] Wan T, Au DWT, Mo J, Chen L, Cheung KM, Kong RYC, Seemann F*. Assessment of parental benzo [a] pyrene exposure-induced cross-generational neurotoxicity and changes in offspring sperm DNA methylome in medaka fish. Environmental epigenetics, 2022, 8(1): 1−12.

[26] Guo J, Mo J, Zhao Q, Han Q, Kanerva M, Iwata H, Li Q*. De novo transcriptomic analysis predicts the effects of phenolic compounds in Ba River on the liver of female sharpbelly (Hemiculter lucidus). Environmental Pollution, 2020, 264: 114642.

获奖情况：

学生培养情况：

2020级生物技术 本科生童永祺（暨南大学攻硕）

2021级生物技术 本科生汤灿（优秀毕业论文，华南师范大学攻硕）

2021级生物技术 本科生汤灿“第六届高校大学生海洋与化学科技实践论坛”优秀墙报奖

2021级生物技术 本科生汤灿“第十届全国大学生生命科学竞赛（科学探究类）”三等奖

2022级海洋科学 研究生吴欣桐（国家励志奖学金、优秀毕业论文，中国海洋大学攻博）