个人简介
林仲旸 LIN ZHONGYANG
主要通过细胞生物学及遗传学等手段，研究弧菌与宿主互作中的表观调控机制、先天免疫记忆的形成与维持机制。以第一作者或通讯作者在《Science Advances》、《Nucleic Acids Research》、《Reviews in Aquaculture》和《the Journal of Immunology》等国际期刊发表论文12篇, 主持国家自然科学基金面上项目1项，广东省面上项目2项。
研究兴趣：
1. 弧菌重编程宿主表观遗传的机制
2. 对虾先天免疫记忆形成的机制及应用
3.以秀丽线虫为模型探究先天免疫记忆的跨代遗传机制
Email：linzy@stu.edu.cn
Personal page：https://www.researchgate.net/profile/Zhongyang-Lin-3?ev=hdr_xprf
https://orcid.org/0000-0001-9376-9553
欢迎拔尖班及菁英班学生加入课题组；
欢迎有志从事表观遗传调控、先天免疫记忆/训练免疫的学生报考研究生。
工作经历：
2022.03 – 至今 汕头大学 Shantou University 副教授 （ Associate Prof.）
2019.04 - 2022.02 香港大学 The University of Hong Kong 博士后 Post-doctoral fellow
学历简介：
2013.01 - 2018.11 香港大学 The University of Hong Kong 博士 Ph.D
2008.09 - 2011.06 汕头大学 Shantou University 硕士 M.s
2004.09 - 2008.06 广东海洋大学 Guangdong Ocean University 学士 B.s
担任课程：
本科生课程： 细胞生物学 (双语)、表观遗传学 (双语)
研究生课程： 表观遗传学进展
研究成果：（#代表并列第一作者，*代表通讯作者，Lin Z为林仲旸）
12. Ng R, Lin Z*, Zhang Y, Ti C, Javed A, Wong J, Fang Q, Leung J, Tang A, Huen M*. R-loop Resolution by ARIP4 Helicase Promotes Androgen-mediated Transcription Induction. Science Advances, 2024, 10, eadm9577.
新闻稿：https://www.stu.edu.cn/info/1085/19806.htm
11.Zhang X, Zhang Z, Zheng Z, Yao D, Zhao Y, Liu Q, Lin Z*, Zhang Y*; biquitination of Hemocyanin Mediated by a Mitochondrial E3 Ubiquitin Ligase Regulates Immune Response in Penaeus vannamei, The Journal of Immunology, 2024,213(12): 1746-1759
10. Chen Z, Tayyab M, Yao D, Aweya J, Zheng Z, Zhao X, Lin Z*, Zhang Y*. (2025). Cell death in crustacean immune defense. Reviews in Aquaculture, 17 (1), e12976. doi: 10.1111/raq.12976
9. Chen H, Huang X, Tayyab M, Zhao M, Yao D, Zheng Z, Zhao X, Zhao Y, Chen X, Zhang B, Yang Q, Zhang Y, Lin Z*. Copper Homeostasis and Its Impact on Innate Immunity in Crustaceans, Reviews in Aquaculture, 2024, 17(1)
8. Hao R, Zhao M, Tayyab M, Lin Z*, Zhang Y*. The mucosal immunity in crustaceans: inferences from other species, Fish & Shellfish Immunology, 2024,109785, https://doi.org/10.1016/j.fsi.2024.109785.
7. Lin Z and Yuen KW. RbAp46/48LIN-53 and HAT-1 are required for initial CENP-AHCP-3 deposition and de novo centromere formation in Caenorhabditis elegans embryos. Nucleic Acids Research, 2021, (https://doi.org/10.1093/nar/gkab217).
6. Lin Z, Xie Y, Nong W, Ren X, Li R, Zhao Z, Hui JH and Yuen KW. Formation of artificial chromosomes in Caenorhabditis elegans and analyses of their segregation in mitosis, DNA sequence composition and holocentromere organization. Nucleic Acids Research, 2021, (https://doi.org/10.1093/nar/gkab690). （6 & 7 为背靠背文章）
新闻稿：https://www.hku.hk/press/press-releases/detail/c_23372.html
https://www.hku.hk/press/press-releases/detail/23372.html
https://m.thepaper.cn/baijiahao_15296701
5. Lin Z and Yuen KW. Construction and analysis of worm artificial chromosomes with de novo holocentromeres in Caenorhabditis elegans. Essays in Biochemistry. 2020; EBC20190067.
4. Ling YH#, Lin Z# and Yuen KW. (2019 接收) Genetic and epigenetic effects on centromere establishment. Chromosoma, 2020，129, 1-24.
3. Lee BC, Lin Z, Yuen KW. RbAp46/48 LIN-53 is required for holocentromere assembly in Caenorhabditis elegans. Cell Reports. 2016, 14: 1819-1828.
2. Cao J#, Lin Z#, Zhang Y, Li S, Wang X. Cloning and characterization of the SpLRR gene from green mud crab, Scylla paramamosain. Fish & Shellfish Immunology, 2013, 34(1): 129-135.
1. Lin Z#, Qiao J#, Zhang Y, Guo L, Huang H, Yan F, Li Y, Wang X. Cloning and characterization of the SpToll gene from green mud crab, Scylla paramamosain. Developmental & Comparative Immunology. 2012; 37(1):164-75.
