个人简介：陈翠英，汕头大学理学院讲师，理学博士，毕业于华南农业大学水生生物学专业，长期从事水产经济动物脂类营养与代谢调控方面的研究，重点关注海水鱼类高不饱和脂肪酸合成与转运调控机制。近年来主持各级科研项目7项，参与各级科研项目10余项，在生物学和水产养殖权威学术期刊《Aquaculture》、《BBA-Molecular and Cell Biology of Lipids》及《Journal of Biological Chemistry》等发表SCI论文20多篇，参编著作1本，获得国家授权发明专利2项，广东省自然科学奖二等奖1项（排名第四）。

邮箱：cychen@stu.edu.cn

7个代表性项目：

（1）国家自然科学基金面上项目，32473178，DHA通过GPR120-miR143/145通路负反馈抑制黄斑蓝子鱼HUFA合成的分子机制研究，2025/01-2028/12，在研，主持。

（2）国家自然科学基金青年基金项目，31702357，miR-145在黄斑蓝子鱼HUFA合成调控中的作用及机制研究，2018/01-2020/12，26万元，结题，主持。

（3）中国博士后科学基金第60批资助项目，2016M602500，蓝子鱼LC-PUFA合成关键miRNAs的筛选及其调控机制研究，2016.04-2018.04，5万元，结题，主持。

（4）广东省科技计划项目，STKJ2021106，青蟹高效配合饲料的研发，2021-10-1至2024-9-30，10万元，在研，主持。

（5）广东省科技计划项目，STKJ202209037，龙须菜琼胶提取废渣回收利用技术的研发与应用，2022/08/10-2025/08/09，10万，在研，主持。

（6）广东省自然科学基金面上项目，2024A1515012777，miR-143/145基因簇参与黄斑蓝子鱼LC-PUFA合成调控的作用与机制研究，2024/01/01-2026/12/31，15万，在研，主持。

（7）企业横向课题，20220224-H，龙须菜琼胶提取废渣饲料化利用开发与应用，2022/12/22-2024/12/31，15万，在研，主持。

代表性发表论文:

(1) Chen, C.Y., Wang, S.Q., Hu, Y., Zhang, M., He, X.D., You, C.H., Wen, X.B., Monroig, Ó., Tocher, D.R., Li, Y.Y. miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα-Srebp1 pathway in the marine teleost Siganus canaliculatus, Journal of Biological Chemistry, 2020, 295:13875–13886.

(2) Chen, C.Y., Zhang, M., Li, Y.Y., Wang, S.Q., Xie, D.Z., Wen, X.B., Hu, Y., Shen, J.J., He, X.D., You, C.H., Tocher, D.R., Monroig, Ó. Identification of miR-145 as a key regulator involved in LC-PUFA biosynthesis by targeting hnf4α in the marine teleost Siganus canaliculatus. Journal of Agricultural and Food Chemistry, 2020, 68: 15123–15133.

(3) Chen, C.Y., Wang, S.Q., Zhang, M., Chen, B.J., You, C.H., Xie, D.Z., Liu, Y., Monroig, Ó., Tocher, D.R., Waiho. K., Li, Y.Y. miR-24 is involved in vertebrate LC-PUFA biosynthesis as demonstrated in marine teleost Siganus canaliculatus. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019, 1864(5): 619.

(4) Chen, C.Y., Zhang, J.Y., Zhang, M., You, C.H., Liu, Y., Wang, S.Q., Li, Y.Y. miR-146a is involved in the regulation of vertebrate LC-PUFA biosynthesis by targeting elovl5 as demonstrated in rabbitfish Siganus canaliculatus. Gene, 2018, 676: 306-314.

(5) Chen, C.Y., Guan, W.T., Xie, Q.M., Chen, G.L., He, X.L., Zhang, H.L., Guo, W.Y., Chen, F., Tan, Y.W., Pan, Q. n-3 essential fatty acids in Nile tilapia, Oreochromis niloticus: Bioconverting LNA to DHA is relatively efficient and LC-PUFA biosynthetic pathway is substrate limited in juvenile fish. Aquaculture, 2018, 495: 513-522.

(6) Chen, C.Y., Chen, J.S., Wang, S.Q., You, C.H., Li, Y.Y. Effects of different dietary ratios of linolenic to linoleic acids or docosahexaenoic to eicosapentaenoic acids on the growth and immune indices in grouper, Epinephelus coioides. Aquaculture, 2017, 473: 153-160.

(7) Chen, C.Y., Sun, B.L., Guan, W.T., Bi, Y.Z., Li, P.Y., Ma, J.Y., Chen, F., Pan, Q., Xie, Q.M. N-3 essential fatty acids in Nile tilapia, Oreochromis niloticus: Effects of linolenic acid on non-specific immunity and anti-inflammatory responses in juvenile fish. Aquaculture, 2016, 450: 250-257.

(8) Chen, C.Y., Sun, B.L., Li, X.X., Li, P.Y., Guan, W.T., Bi, Y.Z., Pan, Q. N-3 essential fatty acids in Nile tilapia, Oreochromis niloticus: Quantification of optimum requirement of dietary linolenic acid in juvenile fish. Aquaculture, 2013, 416-417: 99-104.

(9) Zhang, M.^#, Chen, C.Y.^#, You, C.H., Chen, B.J., Wang, S.Q.*, Li, Y.Y.* Effects of different dietary ratios of docosahexaenoic to eicosapentaenoic acid (DHA/EPA) on the growth, non-specific immune indices, tissue fatty acid compositions and expression of genes related to LC-PUFA biosynthesis in juvenile golden pompano Trachinotus ovatus. Aquaculture, 2019, 505, 488-495.

(10) Guo, H.J.^#, Chen, C.Y.^#, Yan, X., Li, Y.Y., Wen, X.B., You, C.H., Monroig, O., Tocher, D.R., Wang, S.Q. Effects of different dietary oil sources on growth performance, antioxidant capacity and lipid deposition of juvenile golden pompano Trachinotus ovatus. Aquaculture, 2021, 530, 735923.

(11) Liu, L.J. ^#, Chen, C.Y. ^#, Dong, Y.W., Cheng, Y., You, C.H., Wang, S.Q., Ma, H.Y., Li, Y.Y. Insulin activates LC-PUFA biosynthesis of hepatocytes by regulating the PI3K/Akt/mTOR/Srebp1 pathway in teleost Siganus canaliculatus. Comparative Biochemistry and Physiology, Part B, 2022, 260: 110734.

(12) Xie, D. Z.^#, Chen, C.Y. ^#, Dong, Y. W.^#, You, C.H., Wang, S.Q.^*, Monroig, O.^*, Tocher, D.R., Li, Y.Y^*. Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish. Progress in Lipid Research, 2021, 82, 101095.

(13) Zhong, W.J., Chen, .CS., Tan, S.Y., He, X.D., Wang, S.Q., Tocher, D.R., Lin, F., Sun, Z.J., Wen, X.B., Li, Y.Y., Waiho, K., Wu, X.G., Chen, C.Y*. Identification of a novel crustacean vascular endothelial growth factor b-like in the mud crab Scylla paramamosain, and examination of its role in lipid accumulation. Aquaculture, 2023, 575: 739793.

(14) Chen, C.Y., Nie, X.F., Cheng, Y., Shen, J.J., Zhang P.Y., Zhong, W.J., Wang, S.Q., You, C.H., Li, Y.Y. Effects of dietary cholesterol and phospholipid levels on growth performance, antioxidant capacity, and tissue fatty acid in the juvenile mud crab Scylla paramamosain Estampador, 1950 (Decapoda: Brachyura: Portunidae). Journal of Crustacean Biology, 2022, 42, 1–11.

(15) Chen, C.Y., Nie, X.F., Cheng, Y., Shen, J.J., He, X.D., Wang, S.Q., You, C.H., Li, Y.Y. Comparative analysis of growth performance, feed utilization, and antioxidant capacity of juvenile mud crab, Scylia paramamosain, reared at two different conditions. Crustaceana, 2021, 94(8): 1021-1033.

(16) Zhong, W.J., Chen, .CS., Tan, S.Y., He, X.D., Wen, X.B., Wang, S.Q., Tocher, D.R., Waiho, K., Chen, C.Y*. Identification and functional characterization of the Fatp1 gene from mud crab, Scylla paramamosain. Animals, 2024.

专利申请与授权：

（1）陈翠英, 王树启, 游翠红, 张媚, 胡宇. miRNA-sc-miR-145 在鱼类LC-PUFA 合成的应用. 授权日：2022年6月28日，专利号： ZL 202010287943.2

（2）陈翠英，王树启，张鹏元，余金达，孙志杰，林帆. 一种长保质期的拟穴青蟹软颗粒配合饲料及其制备方法。授权日：2023年09月26日，专利号：ZL 2022 10414933.X